Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544794 | 0.85 | ACE (0.45) | ACEMMECPA1ACE2MMP9 | |
| SCHEMBL7542675 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AMMP2 | |
| SCHEMBL7542685 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AMMP2 | |
| SCHEMBL7542673 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AMMP2 | |
| SCHEMBL7541870 | 0.80 | FOLH1 (0.54) | ACEMMECPA1ACE2MMP9 | |
| SCHEMBL7538785 | 0.80 | FOLH1 (0.54) | ACEMMECPA1ACE2MMP9 | |
| SCHEMBL7540008 | 0.79 | MMP3 (0.50) | ACEMMECPA1ACE2MMP9 | |
| SCHEMBL7546158 | 0.76 | FOLH1 (0.53) | ACEMMECPA1ACE2MMP9 | |
| SCHEMBL7547257 | 0.76 | FOLH1 (0.55) | ACEMMECPA1ACE2MMP2 | |
| SCHEMBL7543503 | 0.76 | MMP3 (0.45) | ACEMMECPA1ACE2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |