Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611302 | 0.86 | MTNR1A (0.42) | MTNR1ASMN1; SMN2HPGDRAB9A | |
| SCHEMBL7121703 | 0.86 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL7508213 | 0.86 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL8655361 | 0.81 | HTR2A (0.46) | — | |
| SCHEMBL8658395 | 0.80 | MAOB (0.52) | — | |
| SCHEMBL13855695 | 0.80 | GFER (0.44) | MTNR1ASMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL576925 | 0.77 | KMT2A (0.41) | SMN1; SMN2CTRC | |
| SCHEMBL25608600 | 0.77 | PTGS2 (0.39) | HPGDCTRC | |
| SCHEMBL8655145 | 0.77 | MEN1 (0.43) | SMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL8451797 | 0.77 | MAPKAPK2 (0.39) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912561-B1 | 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2002-12-04 | — | — | EP | disclosed |