Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293113 | 0.79 | TSHR (0.59) | SMN1; SMN2HTTSTAT3TLR8MAPT | |
| SCHEMBL27324326 | 0.77 | MEN1 (0.59) | SMN1; SMN2HTTSTAT3HRH4CNR1 | |
| SCHEMBL28310888 | 0.73 | TLR8 (0.68) | SMN1; SMN2HTTSTAT3HRH4TLR8 | |
| SCHEMBL6629949 | 0.72 | KDM4E (0.51) | SMN1; SMN2HTTSTAT3POLBKDM4E | |
| SCHEMBL17912813 | 0.71 | CYP11B1 (0.56) | SMN1; SMN2MAPTLMNACYP11B1CYP11B2 | |
| SCHEMBL16453464 | 0.71 | NCF1 (0.49) | SMN1; SMN2HTTKDM4E | |
| SCHEMBL6566120 | 0.71 | HTT (0.59) | SMN1; SMN2HTTSTAT3CNR1CNR2 | |
| SCHEMBL8981682 | 0.68 | KMT2A (0.69) | CNR1CNR2KDM4EALDH1A1KMT2A | |
| SCHEMBL7506608 | 0.68 | CYP11B1 (0.47) | HTTCNR1CNR2LMNACYP11B1 | |
| SCHEMBL8548739 | 0.68 | RAB9A (0.69) | SMN1; SMN2HTTHRH4LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |