Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26448041 | 0.83 | SNCA (0.47) | SNCALMNALPLLIPG | |
| SCHEMBL31697629 | 0.83 | SNCA (0.47) | SNCALMNALPLLIPG | |
| SCHEMBL31697630 | 0.79 | HTT (0.52) | SNCALMNAKMT2ALPLLIPG | |
| SCHEMBL26448034 | 0.79 | HTT (0.52) | SNCALMNAKMT2ALPLLIPG | |
| SCHEMBL20552246 | 0.78 | SNCA (0.43) | SNCALMNAKMT2ALPLLIPG | |
| SCHEMBL7539138 | 0.78 | SMN1; SMN2 (0.48) | LMNAKMT2ATP53 | |
| SCHEMBL7534511 | 0.77 | ALDH1A1 (0.51) | LMNAKMT2ATP53 | |
| SCHEMBL6068038 | 0.76 | LMNA (0.49) | LMNAKMT2ATP53 | |
| SCHEMBL7540147 | 0.75 | KMT2A (0.55) | LMNAKMT2A | |
| SCHEMBL19922430 | 0.75 | SNCA (0.47) | SNCAF2F11PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |