Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545150 | 0.92 | PTGS2 (0.63) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7544733 | 0.91 | PTGS2 (0.51) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7537374 | 0.91 | PTGS2 (0.51) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7539478 | 0.91 | PTGS2 (0.48) | PTGS2PTGS1GRM4ALOX5FEN1 | |
| SCHEMBL7539544 | 0.90 | PTGS2 (0.50) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7546410 | 0.90 | PTGS2 (0.49) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7543109 | 0.89 | PTGS2 (0.49) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7045390 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7540499 | 0.88 | PTGS2 (0.48) | PTGS2PTGS1GRM4FEN1ALOX5AP | |
| SCHEMBL7546260 | 0.87 | PTGS2 (0.47) | PTGS2PTGS1GRM4FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, FPR1, PTGES2 | PTGS2 5/4885PTGS1 4/4885GRM4 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.