Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372657 | 0.86 | ACMSD (0.48) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL7552573 | 0.79 | ALDH1A1 (0.53) | HSD17B10ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL7090889 | 0.78 | HSD17B10 (0.66) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL11740275 | 0.76 | ALDH1A1 (0.59) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL7213442 | 0.76 | HSD17B10 (0.50) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL7038229 | 0.76 | ALDH1A1 (0.56) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL11736095 | 0.72 | ALDH1A1 (0.46) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL6300081 | 0.72 | SIRT1 (0.54) | HSD17B10ALDH1A1HPGDTSHRCYP1A2 | |
| SCHEMBL17550131 | 0.72 | POLB (0.72) | HSD17B10ALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL19953793 | 0.71 | KDM4E (0.48) | HSD17B10ALDH1A1HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |