SCHEMBL7545406

SCHEMBL7545406

CC(OC(N)=O)Sc1ccccc1-c1ccccc1C=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.35
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535787 0.88 DRD1 (0.39) DRD1ALDH1A1TSHRHCRTR1HCRTR2
SCHEMBL7539101 0.82 CA12 (0.36) THRBALDH1A1TSHR
SCHEMBL7536344 0.80 MYC (0.42) MEN1LMNAKMT2AALDH1A1
SCHEMBL7535634 0.77 CA12 (0.38) LMNA
SCHEMBL7539093 0.76 ALOX5 (0.35) MEN1LMNATHRBBLMKMT2A
SCHEMBL11288988 0.75 EPHX1 (0.34) MEN1LMNAKMT2AALDH1A1TSHR
SCHEMBL7541920 0.74 TTR (0.40) KMT2ATDP1ALDH1A1
SCHEMBL7535941 0.71 PTGDR2 (0.37) MEN1LMNATHRBBLMKMT2A
SCHEMBL465266 0.70 LMNA (0.41) LMNAALDH1A1TSHR
SCHEMBL6536177 0.69 LMNA (0.46) DRD1MEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 DRD1 681/4885MEN1 3828/4885LMNA 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.