Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.76 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.76 |
| ▸ | PPARG | P37231 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952279 | 0.99 | AGTR1 (0.78) | AGTR1AGTR2PPARGLMNAMEN1 | |
| SCHEMBL9764119 | 0.97 | AGTR1 (0.76) | AGTR1AGTR2PPARGLMNAMEN1 | |
| SCHEMBL7545509 | 0.97 | AGTR1 (0.76) | AGTR1AGTR2PPARGLMNAMEN1 | |
| SCHEMBL28487275 | 0.97 | AGTR1 (0.76) | AGTR1AGTR2PPARGLMNAMEN1 | |
| SCHEMBL29411886 | 0.97 | AGTR1 (0.76) | AGTR1AGTR2PPARGLMNAMEN1 | |
| SCHEMBL13261296 | 0.90 | AGTR1 (0.73) | AGTR1AGTR2PPARGLMNAPDE4D | |
| SCHEMBL13508734 | 0.88 | AGTR1 (0.71) | AGTR1AGTR2PPARGLMNAPDE4D | |
| SCHEMBL9197881 | 0.87 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL28481747 | 0.86 | LMNA (0.81) | AGTR1AGTR2LMNAMEN1KMT2A | |
| SCHEMBL29411883 | 0.86 | LMNA (0.81) | AGTR1AGTR2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837856-B1 | PESTICIDAL TRIS-OXIMINO HETEROCYCLIC COMPOUNDS | BAYER AG (DE) | 2002-06-19 | — | — | EP | disclosed |
| US-6342633-B1 | SULFIDING A CARBONYL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6211240-B1 | INSECTICIDES | NOVARTIS CORPORATION | 2001-04-03 | — | — | US | disclosed |
| EP-0792261-B1 | O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1999-12-22 | — | — | EP | disclosed |
| US-5977182-A | O-benzyl oxime ether derivatives and their use as pesticides | NOVARTIS FINANCE CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |