Triaziquone

Triaziquone

SCHEMBL7545576

CCCCC(C(C)=O)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1.[AlH3]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.32
TTR P02766 1/20 0.32
DNMT1 P26358 1/20 0.32
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
STAT3 P40763 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.30
CHEK1 O14757 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL8491679 0.99 NSD2 (0.33) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL6848459 0.94 GPR84 (0.34) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL6380212 0.94 GPR84 (0.34) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL7946775 0.93 DNMT1 (0.33) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL6381180 0.91 DNMT1 (0.34) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL3086309 0.87 DNMT1 (0.38) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL424867 0.86 DNMT1 (0.39) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL6138445 0.85 DNMT1 (0.38) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL5974054 0.85 DNMT1 (0.38) NSD2TTRDNMT1TP53MAPT
Triaziquone SCHEMBL1569136 0.84 CA2 (0.50) NSD2TTRDNMT1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805186-B1 THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES NOF CORP (JP) 2002-05-29 EP disclosed
EP-0709415-B1 Substrat coated by a base-coat and a clear coat, method of film-forming and coated articles NOF CORP (JP) 2001-07-25 EP disclosed
US-6103387-A THERMOSETTING RESIN COMPRISING A CERAMIC, WHICH GIVES A CURED PRODUCT HAVING EXCELLENT STAIN RESISTANCE, STAIN-REMOVING PROPERTY, WEATHERING RESISTANCE, LIGHT RESISTANCE, CHEMICAL RESISTANCE, MOISTURE RESISTANCE AND APPEARANCE NOF CORPORATION (JP) 2000-08-15 US disclosed
US-6030571-A Methods of molding and molded articles made thereby NOF CORPORATION (JP) 2000-02-29 US disclosed
US-5993909-A COMPRISING EPOXY GROUP CONTAINING MODIFIED POLYESTER AND A COMPOUND CONTAINING FUNCTIONAL GROUPS PER MOLECULE; COATINGS, INKS, ADHESIVES NOF CORPORATION (JP) 1999-11-30 US disclosed
US-5922633-A THERMAL LATENT ACID CATALYST CONSISTS OF AN EPOXY COMPOUND, A SULFUR COMPOUND AND LEWIS ACID NOF CORPORATION (JP) 1999-07-13 US disclosed
EP-0805186-A1 THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES NOF CORPORATION (JP) 1997-11-05 EP disclosed
US-5661219-A AN ACRYLIC COPOLYMER HAVING CARBOXY GROUPS BLOCKED BY A VINYL ETHER, A REACTIVE POLYMER, E.G.HAVING EPOXY GROUPS, AND LEWIS ACID-COMPLEX CATALYST; HIGH SOLIDS; LOW TEMPERATURE CURING; STORAGE STABILITY; MECHANICAL PROPERTIES NOF CORPORATION (JP) 1997-08-26 US disclosed
EP-0643112-B1 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORP (JP) 1997-07-30 EP disclosed
EP-0709415-A2 Curable base-coat composition, method of film-forming and coated articles NOF CORPORATION (JP) 1996-05-01 EP disclosed
EP-0643112-A2 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORPORATION (JP) 1995-03-15 EP disclosed
EP-0282634-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1988-09-21 EP disclosed