SCHEMBL754568

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756168	0.90	IDH1 (0.38)	LIPGHRH3IDH1ALDH1A1
	SCHEMBL755270	0.86	HRH3 (0.38)	ACACBLIPGACACAHRH3IDH1
	SCHEMBL753023	0.85	HRH3 (0.41)	ACACBLIPGACACAHRH3IDH1
	SCHEMBL754428	0.84	LIPG (0.48)	ACACBLTA4HCYP11B1CYP11B2LIPG
	SCHEMBL757191	0.77	HRH3 (0.40)	LIPGHRH3IDH1ALDH1A1SMN1; SMN2
	SCHEMBL2486824	0.76	HRH3 (0.43)	LIPGHRH3IDH1MMP13KDM4E
	SCHEMBL752971	0.74	LIPG (0.49)	LTA4HLIPGHRH3IDH1MMP13
	SCHEMBL755368	0.73	HRH3 (0.39)	LIPGHRH3IDH1MMP13KDM4E
	SCHEMBL751851	0.71	CYP11B1 (0.32)	CYP11B1CYP11B2LIPGIDH1KDM4E
	SCHEMBL13503270	0.70	LIPG (0.51)	LIPGKDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.