SCHEMBL755368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751906	0.89	HRH3 (0.37)	HRH3LIPGIDH1MEN1KMT2A
	SCHEMBL754174	0.85	LIPG (0.46)	HRH3LIPGSCN4AALDH1A1L3MBTL1
	SCHEMBL2486824	0.83	HRH3 (0.43)	HRH3LIPGALDH1A1L3MBTL1IDH1
	SCHEMBL756168	0.83	IDH1 (0.38)	HRH3LIPGSCN4AALDH1A1L3MBTL1
	SCHEMBL757191	0.77	HRH3 (0.40)	HRH3LIPGSCN4AALDH1A1L3MBTL1
	SCHEMBL752929	0.75	CYP4F2 (0.44)	HRH3LIPGMMP13
	SCHEMBL753739	0.73	LIPG (0.43)	HRH3LIPGMEN1KMT2AEGLN1
	SCHEMBL754568	0.73	ACACB (0.40)	HRH3LIPGALDH1A1IDH1SMN1; SMN2
	SCHEMBL751851	0.72	CYP11B1 (0.32)	LIPGALDH1A1IDH1SMN1; SMN2MEN1
	SCHEMBL753023	0.72	HRH3 (0.41)	HRH3LIPGALDH1A1IDH1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.