Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853041 | 0.86 | ALDH1A1 (0.56) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL27594280 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6847857 | 0.76 | ALDH1A1 (0.65) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11302858 | 0.76 | KDM4E (0.57) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL23781693 | 0.75 | ALDH1A1 (0.63) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9131768 | 0.75 | APP (0.53) | ALDH1A1ACACBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7214768 | 0.75 | ALDH1A1 (0.63) | ALDH1A1ACACBMGAMPDGFRBPDGFRA | |
| SCHEMBL11298448 | 0.74 | ABL1 (0.63) | ALDH1A1ACACBKDM4EABL1BCR | |
| SCHEMBL18253192 | 0.73 | ALDH1A1 (0.65) | ALDH1A1ACACBMGAMPDGFRBPDGFRA | |
| SCHEMBL124863 | 0.72 | NPSR1 (0.55) | ALDH1A1KDM4EKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |