Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996660 | 0.84 | HPGD (1.00) | HPGDMAPK1TK1 | |
| SCHEMBL11723021 | 0.76 | SMN1; SMN2 (0.44) | HPGDMAPK1TK1 | |
| SCHEMBL7546901 | 0.73 | TK1 (0.42) | HPGDMAPK1TK1 | |
| SCHEMBL27734975 | 0.73 | HPGD (0.61) | HPGDMAPK1 | |
| SCHEMBL7821405 | 0.73 | HPGD (0.69) | HPGDMAPK1TK1 | |
| SCHEMBL7834073 | 0.73 | HPGD (0.76) | HPGDMAPK1TK1 | |
| SCHEMBL7549198 | 0.72 | TYMP (0.43) | HPGDMAPK1TK1 | |
| SCHEMBL24495513 | 0.71 | DAO (0.72) | HPGDMAPK1 | |
| SCHEMBL4172709 | 0.71 | HPGD (0.67) | HPGDMAPK1TK1 | |
| SCHEMBL7554990 | 0.71 | TK1 (0.47) | HPGDMAPK1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165554-A1 | NEW ENDOTHELIN CONVERTING ENZYME INHIBITORS, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000061579-A1 | NEW ENDOTHELIN CONVERTING ENZYME INHIBITORS, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-19 | — | — | WO | disclosed |