SCHEMBL754634

SCHEMBL754634

O=S(=O)(C(I)(I)c1ccc(Cl)cc1)C(I)(I)c1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.42
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
CA9 Q16790 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
TSHR P16473 2/20 0.39
CA12 O43570 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA13 Q8N1Q1 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754508 0.76 CA2 (0.47) CA1CA2CA9CA12CA5A
SCHEMBL751741 0.76 CA1 (0.47) CYP3A4ALDH1A1CA1CA2CA9
SCHEMBL751562 0.76 ALDH1A1 (0.50) MAPK1CYP3A4ALDH1A1CA1CA2
SCHEMBL753849 0.75 CA1 (0.43) ALDH1A1CA1CA2CA9MEN1
SCHEMBL750528 0.73 MAPK1 (0.44) MAPK1CYP3A4ALDH1A1CA1CA2
SCHEMBL27882815 0.71 MEN1 (0.39) MAPK1CYP3A4ALDH1A1MEN1KMT2A
SCHEMBL754522 0.71 CA1 (0.55) ALDH1A1CA1CA2CA9CA12
SCHEMBL753731 0.69 ESR1 (0.45) ALDH1A1CA1CA2HSD11B1ACHE
SCHEMBL750643 0.67 FLT1 (0.36) MAPK1CYP3A4ALDH1A1MEN1KMT2A
SCHEMBL20368835 0.67 MEN1 (0.56) MAPK1MEN1KMT2ATSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
US-5773157-A SUBSTRATE WITH MAGNETIC COATING LAYER OF POWDERS AND BINDERS TEIJIN LIMITED (JP) 1998-06-30 US disclosed
EP-0640959-B1 Magnetic recording medium with fungiresistance and process for manufacturing same TEIJIN LTD (JP) 1998-01-07 EP disclosed
US-5545401-A PREVENTS SEXUALLY TRANSMITTED DISEASES; INTRODUCED TO VAGINA, PRIOR TO INTERCOURSE IN THE FORM OF GEL OR FOAM SHANBROM TECHNOLOGIES, LLC 1996-08-13 US disclosed
EP-0640959-A1 Magnetic recording medium with fungiresistance and process for manufacturing same TEIJIN LIMITED (JP) 1995-03-01 EP disclosed
US-5370869-A Antimicrobial preservation of platelets and blood factors SHANBROM TECHNOLOGIES, LLC 1994-12-06 US disclosed
US-5300520-A With diphenyl alkane-type compound to improve durability TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
EP-0559856-A4 ANTIMICROBIAL PRESERVATION OF PLATELETS AND BLOOD FACTORS 1993-11-10 EP disclosed
EP-0559856-A1 ANTIMICROBIAL PRESERVATION OF PLATELETS AND BLOOD FACTORS Shanbrom, Edward (US) 1993-09-15 EP disclosed
WO-1993004731-A1 IODINE-IODIDE TREATMENT OF RED BLOOD CELLS SHANBROM EDWARD (US) 1993-03-18 WO disclosed
WO-1993004730-A1 IODIDE-IODINE-PEROXIDE THERAPY SHANBROM EDWARD (US) 1993-03-18 WO disclosed
WO-1993004678-A1 ANTIMICROBIAL PRESERVATION OF PLATELETS AND BLOOD FACTORS SHANBROM EDWARD (US) 1993-03-18 WO disclosed
EP-0500893-A1 PRESERVATION OF BLOOD, TISSUES AND BIOLOGICAL FLUIDS Shanbrom, Edward (US) 1992-09-02 EP disclosed
WO-1992004031-A1 PRESERVATION OF BLOOD, TISSUES AND BIOLOGICAL FLUIDS SHANBROM EDWARD (US) 1992-03-19 WO disclosed
EP-0454431-A1 Wood preservative composition Takeda Chemical Industries, Ltd. (JP) 1991-10-30 EP disclosed
US-4228124-A Fumigating method and apparatus EARTH CHEMICAL COMPANY (JP) 1980-10-14 US disclosed
US-4171340-A BLOWING AGENT WHICH DECOMPOSES TO NITROGEN EARTH CHEMICAL COMPANY, LTD. (JP) 1979-10-16 US disclosed
US-4163038-A ACTIVE INGREDIENT AND BLOWING AGENT EARTH CHEMICAL COMPANY, LIMITED (JP) 1979-07-31 US disclosed
US-4018611-A Non-yellowing antimicrobial compositions comprising diiodomethyl sulfones METALORGANA ETABLISSEMENT (FL) 1977-04-19 US disclosed