Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CCR1 | P32246 | 3/20 | 0.51 |
| ▸ | CCR5 | P51681 | 3/20 | 0.51 |
| ▸ | CCR8 | P51685 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551921 | 0.90 | CCR1 (0.51) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL7548609 | 0.79 | GPR39 (0.44) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL308968 | 0.74 | HSP90AA1 (0.43) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL7546716 | 0.74 | CCR1 (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL308214 | 0.73 | KDM4E (0.47) | KDM4ESMN1; SMN2KDM6BKDM4AKDM5C | |
| Terpyridine SCHEMBL30610403 | 0.72 | KDM4E (0.90) | KDM4ECCR1CCR5CCR8LMNA | |
| Terpyridine SCHEMBL57442 | 0.72 | KDM4E (1.00) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL7964803 | 0.72 | KDM4E (1.00) | KDM4ECCR1CCR5CCR8LMNA | |
| Terpyridine SCHEMBL29357603 | 0.72 | KDM4E (1.00) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL30172832 | 0.72 | KDM4E (1.00) | KDM4ECCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885233-B1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2002-06-19 | — | — | EP | disclosed |