SCHEMBL308968

SCHEMBL308968

NCCCCCCNc1ccnc(-c2ccccn2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.43
HSP90AB1 P08238 2/20 0.43
HRH1 P35367 1/20 0.43
NPY5R Q15761 6/20 0.42
METAP1 P53582 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
BLM P54132 1/20 0.40
HIF1A Q16665 1/20 0.40
DOHH Q9BU89 1/20 0.40
P4HTM Q9NXG6 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
RAD52 P43351 1/20 0.39
FERMT2 Q96AC1 1/20 0.39
SYK P43405 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7156867 0.86 KDR (0.36) HSP90AA1HSP90AB1NPY5RDYRK1BRAD52
Hydrochloric Acid SCHEMBL1805727 0.86 KDR (0.36) HSP90AA1HSP90AB1NPY5RDYRK1BRAD52
SCHEMBL308214 0.81 KDM4E (0.47) KDM4EKDM6BKDM4AKDM5CKDM4C
SCHEMBL4097453 0.78 ALDH1A1 (0.48) KDM4ELMNAKDM6BKDM4AKDM5C
SCHEMBL1071320 0.78 FERMT2 (0.45) KDM4ECYP1A2CCR1CCR5CCR8
Dipyridyl SCHEMBL5579842 0.78 KDM4E (0.61) HSP90AA1HRH1METAP1KDM4ELMNA
Dipyridyl SCHEMBL25299271 0.78 CCR1 (0.42) NPY5RMETAP1KDM4ELMNACYP1A2
Dipyridyl SCHEMBL5535016 0.76 CCR1 (0.44) CYP1A2CCR1CCR5CCR8KARS1
Dipyridyl SCHEMBL5312377 0.76 CCR1 (0.44) CYP1A2CCR1CCR5CCR8KARS1
Dipyridyl SCHEMBL25304624 0.75 CCR1 (0.40) NPY5RMETAP1KDM4ECYP1A2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10219730-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2019-03-05 US disclosed
US-10219730-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2019-03-05 US disclosed
US-20160296147-A1 Redox Polymers THERASENSE, INC. 2016-10-13 US disclosed
US-20160296147-A1 Redox Polymers THERASENSE, INC. 2016-10-13 US disclosed
US-9320467-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2016-04-26 US disclosed
US-9320467-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2016-04-26 US disclosed
US-20140364710-A1 Redox Polymers THERASENSE, INC. 2014-12-11 US disclosed
US-20140364710-A1 Redox Polymers THERASENSE, INC. 2014-12-11 US disclosed
US-8828204-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2014-09-09 US disclosed
US-8828204-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2014-09-09 US disclosed
US-7090756-B2 Controller for redox system THERASENSE INC. (US) 2006-08-15 US disclosed
US-6975893-B2 Mass transport limited in vivo analyte sensor THERASENSE, INC. (US) 2005-12-13 US disclosed
EP-1230249-B1 TRANSITION METAL COMPLEXES WITH BIDENTATE LIGAND HAVING AN IMIDAZOLE RING THERASENSE INC (US) 2004-06-02 EP disclosed
US-20040040840-A1 Controller for redox system THERASENSE, INC. 2004-03-04 US disclosed
US-6605200-B1 Charge transfer compounds comprising polymers such as polyvinylpyridine and/or copolymers coupled to osmium compounds, used as biosensors in redox systems THERASENSE, INC. 2003-08-12 US disclosed
US-6605201-B1 Charge transfer compounds comprising osmium compounds coupled to polymers, used as biosensors THERASENSE, INC. 2003-08-12 US disclosed
EP-1230249-A1 TRANSITION METAL COMPLEXES WITH BIDENTATE LIGAND HAVING AN IMIDAZOLE RING Therasense, Inc. (US) 2002-08-14 EP disclosed
EP-1230248-A2 TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN Therasense, Inc. (US) 2002-08-14 EP disclosed
WO-2001036430-A1 TRANSITION METAL COMPLEXES WITH BIDENTATE LIGAND HAVING AN IMIDAZOLE RING THERASENSE, INC. (US) 2001-05-25 WO disclosed
WO-2001036660-A2 TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN THERASENSE, INC. (US) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040040840-A1 Controller for redox system OTC, ME3, PPOX HSP90AA1 2588/4885HSP90AB1 2576/4885HRH1 1747/4885
US-10219730-B2 Redox polymers PPOX, OTC, ME3 HSP90AA1 2769/4885HSP90AB1 2774/4885HRH1 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.