Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549562 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6557770 | 0.71 | ADRA2C (0.34) | — | |
| Hydrochloric Acid SCHEMBL6066830 | 0.70 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL27933331 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL1387828 | 0.70 | CFTR (0.38) | — | |
| Bromide SCHEMBL27948802 | 0.67 | HTR2A (0.35) | — | |
| Iodide SCHEMBL27948786 | 0.67 | LMNA (0.33) | — | |
| Hydrochloric Acid SCHEMBL5392225 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29281384 | 0.67 | LMNA (0.34) | — | |
| Fluoride Ion SCHEMBL27932977 | 0.67 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798306-B1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM CO (US) | 2002-05-22 | — | — | EP | claimed |