Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150295 | 0.74 | — | — | |
| SCHEMBL12747210 | 0.70 | RAB9A (0.42) | LMNA | |
| SCHEMBL17595984 | 0.70 | KDM4E (0.37) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL27579914 | 0.69 | — | — | |
| SCHEMBL854995 | 0.69 | CYP1A2 (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL17825204 | 0.69 | GABRA1 (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6625545 | 0.69 | SLC6A3 (0.38) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1877939 | 0.69 | KMT2A (0.50) | KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL15273778 | 0.67 | — | — | |
| SCHEMBL14038643 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468995-B1 | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0667868-B1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |