SCHEMBL754675

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754735	0.86	SMN1; SMN2 (0.43)	MEN1KMT2AHPGDRAB9ATP53
	SCHEMBL753035	0.76	NMUR2 (0.50)	CYP2C19HSD17B10MEN1KMT2AHPGD
	SCHEMBL752165	0.75	RAB9A (0.46)	HSD17B10MEN1KMT2AHPGDRAB9A
	SCHEMBL753812	0.70	NPC1 (0.46)	HPGDRAB9ATP53SMN1; SMN2L3MBTL1
	SCHEMBL12266074	0.70	NPC1 (0.46)	HPGDRAB9ATP53SMN1; SMN2L3MBTL1
	SCHEMBL12265972	0.69	RAB9A (0.43)	CYP2C19HPGDRAB9ATP53SMN1; SMN2
	SCHEMBL825685	0.69	NR1I3 (0.46)	MEN1KMT2AHPGDRAB9ATP53
	SCHEMBL14046413	0.68	NPC1 (0.44)	HSD17B10KMT2AHPGDRAB9ATP53
	SCHEMBL13218214	0.68	TP53 (0.42)	MEN1KMT2AHPGDRAB9ATP53
	SCHEMBL4277845	0.68	MAPT (0.42)	HPGDRAB9ATP53SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.