SCHEMBL7546759

SCHEMBL7546759

Cc1cccc(C(=O)S(=O)(=O)c2ccccc2)c1C(=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.45
ALDH1A1 P00352 4/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
KAT6A Q92794 1/20 0.43
HPGD P15428 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.38
ACLY P53396 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
AKR1B10 O60218 1/20 0.37
TRPA1 O75762 1/20 0.37
ABCB11 O95342 1/20 0.37
DHFR P00374 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777052 0.86 HPGD (0.46) MYCALDH1A1GAAMAPTKAT6A
SCHEMBL9772386 0.76 FFAR4 (0.50) ALDH1A1MAPTHPGDKDM4EKMT2A
SCHEMBL7041793 0.70 CYP3A4 (0.48) MYCALDH1A1HPGDKDM4EHSD17B10
SCHEMBL14831125 0.69 ALDH1A1 (0.61) MYCALDH1A1HPGDKDM4EHSD17B10
SCHEMBL29215698 0.68 AKR1C3 (0.59) MYCALDH1A1GAAMAPTHPGD
SCHEMBL776957 0.68 HSD11B1 (0.62) ALDH1A1GAAMAPTKMT2APOLB
SCHEMBL777972 0.68 KAT6A (0.57) ALDH1A1MAPTKAT6AHPGDKMT2A
SCHEMBL5187614 0.68 HSD11B1 (0.52) ALDH1A1MAPTKAT6AHPGDKDM4E
SCHEMBL3039645 0.68 ALDH1A1 (0.59) MYCALDH1A1MAPTHPGDHSD17B10
Phthalic Acid SCHEMBL10989143 0.67 CYP3A4 (0.65) MYCALDH1A1HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819981-B1 Radiation sensitive resin composition JSR CORP (JP) 2002-06-05 EP disclosed