SCHEMBL7546799

SCHEMBL7546799

Cc1ncc(OCCC(C)CCCC(C)C)cn1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
FDPS P14324 2/20 0.41
ALOX5 P09917 1/20 0.39
GGPS1 O95749 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
RARB P10826 1/20 0.34
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX2 P34913 1/20 0.33
GSTO1 P78417 1/20 0.33
BLM P54132 1/20 0.33
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16997128 0.86 TDP1 (0.50) LMNATDP1MAPK1SMN1; SMN2NPC1
SCHEMBL7543086 0.83 TDP1 (0.42) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL7543027 0.83 TDP1 (0.42) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL6857008 0.80 TDP1 (0.58) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL16340342 0.80 TDP1 (0.58) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL14596742 0.77 FDPS (0.43) FDPSALOX5GGPS1TDP1MAPK1
SCHEMBL14596332 0.77 FDPS (0.43) FDPSALOX5GGPS1TDP1MAPK1
SCHEMBL7536898 0.76 KCNA3 (0.52) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL4762110 0.76 KCNA3 (0.52) LMNAFDPSALOX5GGPS1TDP1
SCHEMBL7536703 0.75 CHRNB2 (0.55) FDPSALOX5GGPS1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1204320-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS Bioparken AS (NO) 2002-05-15 EP claimed
WO-2001006853-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS BIOPARKEN AS (NO) 2001-02-01 WO claimed
EP-1204413-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS Bioparken AS (NO) 2002-05-15 EP disclosed
EP-1204320-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS Bioparken AS (NO) 2002-05-15 EP disclosed
WO-2001006853-A2 NOVEL JUVENILE HORMONE ANALOGUES AND THEIR USE AS ANTIFOULING AGENTS BIOPARKEN AS (NO) 2001-02-01 WO disclosed
WO-2001007047-A2 CONTROL OF CRUSTACEAN INFESTATION OF AQUATIC ANIMALS BIOPARKEN AS (NO) 2001-02-01 WO disclosed