SCHEMBL7546809

SCHEMBL7546809

CC(SC(=O)c1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.44
NPSR1 Q6W5P4 3/20 0.44
RXFP1 Q9HBX9 2/20 0.44
GPR139 Q6DWJ6 1/20 0.42
MAPT P10636 3/20 0.42
LMNA P02545 2/20 0.42
XBP1 P17861 1/20 0.42
ATM Q13315 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAP2K7 O14733 1/20 0.41
ELANE P08246 1/20 0.41
CDC25A P30304 1/20 0.41
CDC25B P30305 1/20 0.41
PRNP P04156 1/20 0.41
MAPK10 P53779 1/20 0.41
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
TSHR P16473 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6575624 1.00 SMN1; SMN2 (0.44) SMN1; SMN2NPSR1RXFP1GPR139MAPT
SCHEMBL6578239 1.00 SMN1; SMN2 (0.44) SMN1; SMN2NPSR1RXFP1GPR139MAPT
Hydrochloric Acid SCHEMBL11106436 0.98 SMN1; SMN2 (0.42) SMN1; SMN2NPSR1RXFP1GPR139MAPT
SCHEMBL11046996 0.84 KMT2A (0.44) SMN1; SMN2NPSR1GPR139MAPTLMNA
SCHEMBL16044915 0.83 MAPT (0.45) SMN1; SMN2NPSR1GPR139MAPTLMNA
SCHEMBL6057193 0.83 CES2 (0.50) SMN1; SMN2NPSR1GPR139MAPTLMNA
SCHEMBL13533998 0.82 SMN1; SMN2 (0.41) SMN1; SMN2NPSR1RXFP1MAPTLMNA
SCHEMBL6830394 0.81 LMNA (0.44) SMN1; SMN2NPSR1GPR139MAPTLMNA
SCHEMBL4065108 0.80 CES2 (0.42) SMN1; SMN2NPSR1GPR139MAPTLMNA
SCHEMBL4065115 0.80 CES2 (0.42) SMN1; SMN2NPSR1GPR139MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105713150-B A kind of preparation method and applications of the polycarboxylate water-reducer of resistance to sulfate 江苏苏博特新材料股份有限公司 2018-06-26 CN claimed
CN-105712650-B A kind of preparation method of strong adaptability polycarboxylate water-reducer 江苏苏博特新材料股份有限公司 2018-06-26 CN claimed
CN-105713154-B A kind of preparation method of Early-strength polycarboxylate superplasticizer 江苏苏博特新材料股份有限公司 2018-06-26 CN claimed
CN-108084363-A A kind of preparation method of reinforcing type polycarboxylic acid water-reducing agent 科之杰新材料集团有限公司 2018-05-29 CN claimed
CN-108034024-A A kind of preparation method of high-slump-retentionpolycarboxylate polycarboxylate water reducer 科之杰新材料集团有限公司 2018-05-15 CN claimed
CN-108034025-A A kind of preparation method of high-dispersity polycarboxylic acid water reducing agents 科之杰新材料集团有限公司 2018-05-15 CN claimed
CN-105713150-A Method for preparing sulfate-resistant polycarboxylate water-reducing agents and application thereof 江苏苏博特新材料股份有限公司 2016-06-29 CN claimed
CN-105713154-A Preparation method of early-strength polycarboxylic acid water reducer 江苏苏博特新材料股份有限公司 2016-06-29 CN claimed
CN-105712650-A Method for preparing high-adaptability polycarboxylate water-reducing agent 江苏苏博特新材料股份有限公司 2016-06-29 CN claimed
CN-104744970-A Calcium carbonate/comb-like polyether block polyacrylic acid copolymer slurry and preparation method thereof JIANGSU SUBOTE NEW MAT CO LTD 2015-07-01 CN claimed
CN-104693663-A Aluminum oxide/pectinate polyether block polyacrylic acid copolymer suspension system and preparation method thereof JIANGSU SUBOTE NEW MAT CO LTD 2015-06-10 CN claimed
CN-104311761-A Comb-type polyether block polyacrylic copolymer and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-01-28 CN claimed
US-4224457-A Process for manufacturing optically active sulfur-containing carboxylic acid SANTEN PHARMACEUTICAL CO., LTD. (JP) 1980-09-23 US claimed
CN-119192444-A Water-soluble polymer, preparation method thereof and application thereof in grinding composition 武汉鼎泽新材料技术有限公司 2024-12-27 CN disclosed
CN-111615405-B Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2023-11-28 CN disclosed
CN-110358021-A A kind of cross-linking type wet mixing mortar plasticity-maintaining agent and preparation method thereof 科之杰新材料集团有限公司 2019-10-22 CN disclosed
EP-0250013-A1 Technetium chelates to be used for determining the renal function MALLINCKRODT, INC.(a Missouri corporation) (US) 1987-12-23 EP disclosed
US-4460601-A Dipeptides having a methionine residue and possessing a protective action for the liver MAGGIONI FARMACEUTICI, S.P.A. (IT) 1984-07-17 US disclosed
US-4256761-A Antihypertensive amides USV PHARMACEUTICAL CORPORATION (US) 1981-03-17 US disclosed
US-4224457-A Process for manufacturing optically active sulfur-containing carboxylic acid SANTEN PHARMACEUTICAL CO., LTD. (JP) 1980-09-23 US disclosed