⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540467 | 0.72 | — | — | |
| SCHEMBL5725464 | 0.67 | — | — | |
| SCHEMBL7568643 | 0.64 | PGR (0.35) | — | |
| SCHEMBL11390351 | 0.61 | — | — | |
| SCHEMBL7624027 | 0.60 | SIGMAR1 (0.34) | — | |
| SCHEMBL22954157 | 0.60 | — | — | |
| SCHEMBL7054011 | 0.56 | — | — | |
| SCHEMBL21074921 | 0.51 | — | — | |
| SCHEMBL24720307 | 0.51 | — | — | |
| SCHEMBL321091 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | claimed |
| CN-1179753-C | Contraceptive compositions contaiing antiprogesting and progestinic | — | 2004-12-15 | — | — | CN | disclosed |
| CN-1145618-C | Cyclocarbamate derivatives as progesterone receptor modulators | �Ʒ� | 2004-04-14 | — | — | CN | disclosed |
| CN-1133635-C | Cyanopyrroles for binding progesterone receptors | �Ʒ� | 2004-01-07 | — | — | CN | disclosed |
| CN-1131856-C | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PRODUCTS CORP. (US) | 2003-12-24 | — | — | CN | disclosed |
| CN-1349517-A | Cyclocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349415-A | Contraceptive compositions contaiing antiprogesting and progestinic | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349531-A | Cyanopyrroles as progesterone receptor agonists | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| EP-1173426-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066571-A1 | CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |