SCHEMBL7568643

SCHEMBL7568643

Cc1cc(Br)cc(C2=CC(C)(C)C=CC2)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27470114 0.83 PGR (0.36) PGR
SCHEMBL7562608 0.77 PGR (0.37) PGR
SCHEMBL27455030 0.76 PGR (0.36) PGR
SCHEMBL27472101 0.69 IKBKB (0.30)
SCHEMBL11808958 0.67 ALDH1A1 (0.43) PGR
SCHEMBL30472802 0.67 ALDH1A1 (0.43) PGR
SCHEMBL27455026 0.67 PGR (0.36) PGR
SCHEMBL7624027 0.66 SIGMAR1 (0.34)
SCHEMBL7543866 0.66 LPL (0.33)
SCHEMBL7562811 0.66 PGR (0.36) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1179753-C Contraceptive compositions contaiing antiprogesting and progestinic 2004-12-15 CN disclosed
CN-1145618-C Cyclocarbamate derivatives as progesterone receptor modulators �Ʒ� 2004-04-14 CN disclosed
CN-1131856-C Cyclothiocarbamate derivatives as progesterone receptor modulators AMERICAN HOME PRODUCTS CORP. (US) 2003-12-24 CN disclosed
CN-1349517-A Cyclocarbamate derivatives as progesterone receptor modulators AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
CN-1349415-A Contraceptive compositions contaiing antiprogesting and progestinic AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
CN-1349516-A Cyclothiocarbamate derivatives as progesterone receptor modulators AMERICAN HOME PROD (US) 2002-05-15 CN disclosed
EP-1175411-A1 CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS American Home Products Corporation (US) 2002-01-30 EP disclosed
WO-2000066570-A1 CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed