Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 7/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476412 | 1.00 | KCNQ2 (0.73) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL4264901 | 0.87 | KCNQ2 (0.55) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL29384236 | 0.85 | KCNQ2 (1.00) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL2761225 | 0.85 | KCNQ2 (1.00) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL23567578 | 0.84 | KCNQ2 (0.55) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL29546311 | 0.84 | KCNQ2 (0.55) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL11490783 | 0.82 | KCNQ2 (0.53) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL28767884 | 0.79 | KCNQ2 (0.49) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL11493859 | 0.78 | KCNQ2 (0.49) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL13002451 | 0.77 | KCNQ2 (0.82) | KCNQ2CYP3A4TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656340-B | Aromatized chain transfer reagent and preparation method thereof | 北京大学 | 2023-03-21 | — | — | CN | claimed |
| CN-114656340-A | Aromatized chain transfer reagent and preparation method thereof | 北京大学 | 2022-06-24 | — | — | CN | claimed |
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-114656340-B | Aromatized chain transfer reagent and preparation method thereof | 北京大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-114656340-A | Aromatized chain transfer reagent and preparation method thereof | 北京大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-100509740-C | 10,10-dibenzyl anthrone and derivative and synthetic method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-1858033-A | 10,10-dibenzyl anthrone and its derivative and synthetic method | GUANGZHOU INST CHEMISTRY CAS (CN) | 2006-11-08 | — | — | CN | disclosed |
| CN-1858033-A | 10,10-dibenzyl anthrone and its derivative and synthetic method | GUANGZHOU INST CHEMISTRY CAS (CN) | 2006-11-08 | — | — | CN | disclosed |
| CN-1858033-A | 10,10-dibenzyl anthrone and its derivative and synthetic method | GUANGZHOU INST CHEMISTRY CAS (CN) | 2006-11-08 | — | — | CN | disclosed |
| US-6410754-B1 | OPTIC LENSES (GLASSES, SUNGLASSES); HIGH COLORABILITY AND SENSITIVITY TO ACTIVATING IRRADIATION | FLAMEL TECHNOLOGIES (FR) | 2002-06-25 | — | — | US | disclosed |
| US-20020049341-A1 | PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | FLAMEL TECHNOLOGIES (FR) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049341-A1 | PHOTOCHROMIC SPIROPYRANS, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | ALDH1A2, RB1, CRYAA | KCNQ2 1586/4885CYP3A4 217/4885TSHR 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.