Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619175 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL60339 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL60602 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL284844 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL3174758 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL58854 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL258570 | 1.00 | SIGMAR1 (0.42) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| Methane SCHEMBL28682737 | 0.98 | SIGMAR1 (0.41) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL444584 | 0.98 | SIGMAR1 (0.43) | SIGMAR1NPC1JAK2RAB9APAX8 | |
| SCHEMBL58869 | 0.94 | HTR1B (0.46) | SIGMAR1HTR1BALDH1A1KMT2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216224-A2 | METHOD OF MANUFACTURING ALKYLATED PHENYLNAPHTHYLAMINE COMPOSITIONS; AND PRODUCTS | Noveon IP Holdings Corp. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023343-A2 | METHOD OF MANUFACTURING ALKYLATED PHENYLNAPHTHYLAMINE COMPOSITIONS; AND PRODUCTS | NOVEON IP HOLDINGS CORP. (US) | 2001-04-05 | — | — | WO | disclosed |