SCHEMBL58869

SCHEMBL58869

CCCCN(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.46
SIGMAR1 Q99720 4/20 0.44
HTR1D P28221 1/20 0.43
DHFR P00374 2/20 0.42
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
CASP1 P29466 1/20 0.41
BRCA1 P38398 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ELANE P08246 1/20 0.40
BCHE P06276 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444584 0.95 SIGMAR1 (0.43) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL7547467 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL9619175 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL60602 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL58854 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL258570 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL284844 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL3174758 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
SCHEMBL60339 0.94 SIGMAR1 (0.42) HTR1BSIGMAR1HTR1DDHFRCYP1A2
Methane SCHEMBL28682737 0.92 SIGMAR1 (0.41) HTR1BSIGMAR1HTR1DDHFRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 771 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082383-A Antiwear and corrosion-resistant lubricating oil and preparation method thereof 济宁动力油业有限公司 2025-06-03 CN claimed
CN-119286570-A Preparation method of aromatic amine oligomeric coupling antioxidant and lubricating oil composition 中国石油化工股份有限公司 2025-01-10 CN claimed
CN-117511639-B Composite lubricating oil and preparation method thereof 广州众联晟通科技有限公司 2024-03-22 CN claimed
CN-117511639-A Composite lubricating oil and preparation method thereof 广州众联晟通科技有限公司 2024-02-06 CN claimed
CN-114752430-B Vacuum pump oil 出光兴产株式会社 2023-06-09 CN claimed
CN-109477029-B Vacuum pump oil 出光兴产株式会社 2022-06-17 CN claimed
CN-110392730-B Mineral oil base oil and vacuum pump oil 出光兴产株式会社 2022-04-26 CN claimed
CN-111233829-A Preparation method of nicotine with optical activity 深圳黑尔格科技有限公司 2020-06-05 CN claimed
US-20190277339-A1 COMPOSITION OF HIGH PERFORMANCE BEARING OIL FOR STEEL PLANTS INDIAN OIL CORPORATION LIMITED (IN) 2019-09-12 US claimed
EP-3536768-A1 NOVEL COMPOSITION OF HIGH PERFORMANCE BEARING OIL FOR STEEL PLANTS Indian Oil Corporation Limited (IN) 2019-09-11 EP claimed
CN-104769087-B Grease composition 出光兴产株式会社 2018-07-03 CN claimed
CN-108165352-A A kind of lubricant composition containing biology base, without sulphur, without phosphorus organo-tin compound 杭州聚星新材料科技有限公司 2018-06-15 CN claimed
CN-105051219-B heat treatment oil composition 出光兴产株式会社 2017-09-12 CN claimed
CN-104145010-B Lubricating oil composition 出光兴产株式会社 2016-08-31 CN claimed
US-20260139196-A1 RUST-PREVENTIVE LUBRICATING OIL COMPOSITION HI LEX CORP (JP) 2026-05-21 US disclosed
US-12606729-B2 Use of polymeric-inorganic nanoparticle compositions as heat transfer fluids in battery or other electrical equipment systems EVONIK OPERATIONS GMBH (DE) 2026-04-21 US disclosed
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT ExxonMobil Technology and Engineering Company (US) 2026-03-19 US disclosed
WO-1996037583-A1 LUBRICATING OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1996-11-28 WO disclosed
EP-0719853-A2 Fluid composition for use in fluid coupling Tonen Corporation (JP) 1996-07-03 EP disclosed
WO-1995027022-A1 LUBRICATION OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1995-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606729-B2 Use of polymeric-inorganic nanoparticle compositions as heat transfer fluids in battery or other electrical equipment systems ADH1A, MMAB, ACR HTR1B 2830/4885SIGMAR1 3199/4885HTR1D 3953/4885
US-20260139196-A1 RUST-PREVENTIVE LUBRICATING OIL COMPOSITION SRRT, SCD, SUGT1 HTR1B 4583/4885SIGMAR1 395/4885HTR1D 3620/4885
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT RAF1, PFKP, TP53RK HTR1B 3206/4885SIGMAR1 4678/4885HTR1D 1849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.