SCHEMBL444584

SCHEMBL444584

CCCCCN(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.43
HTR1B P28222 3/20 0.41
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR1D P28221 1/20 0.40
NPC1 O15118 1/20 0.39
JAK2 O60674 1/20 0.39
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DHFR P00374 2/20 0.39
CYP1A2 P05177 1/20 0.38
APAF1 O14727 1/20 0.38
CASP3 P42574 1/20 0.38
CASP6 P55212 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258570 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL284844 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL60339 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL7547467 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL3174758 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL9619175 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL60602 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL58854 0.98 SIGMAR1 (0.42) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
Methane SCHEMBL28682737 0.97 SIGMAR1 (0.41) SIGMAR1HTR1BALDH1A1KMT2AHTR1D
SCHEMBL58869 0.95 HTR1B (0.46) SIGMAR1HTR1BALDH1A1KMT2AHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752430-B Vacuum pump oil 出光兴产株式会社 2023-06-09 CN claimed
CN-109477029-B Vacuum pump oil 出光兴产株式会社 2022-06-17 CN claimed
CN-110392730-B Mineral oil base oil and vacuum pump oil 出光兴产株式会社 2022-04-26 CN claimed
CN-104769087-B Grease composition 出光兴产株式会社 2018-07-03 CN claimed
CN-108165352-A A kind of lubricant composition containing biology base, without sulphur, without phosphorus organo-tin compound 杭州聚星新材料科技有限公司 2018-06-15 CN claimed
US-12606729-B2 Use of polymeric-inorganic nanoparticle compositions as heat transfer fluids in battery or other electrical equipment systems EVONIK OPERATIONS GMBH (DE) 2026-04-21 US disclosed
EP-4715960-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT Dr. Ing. h.c. F. Porsche Aktiengesellschaft (DE) 2026-03-25 EP disclosed
EP-4715023-A1 HEAT TRANSFER FLUID ExxonMobil Technology and Engineering Company (US) 2026-03-25 EP disclosed
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT ExxonMobil Technology and Engineering Company (US) 2026-03-19 US disclosed
US-20260071133-A1 HYDRAULIC LUBRICANT FORMULATIONS WITH HIGH FLASH POINT AND IMPROVED SHEAR STABILITY EVONIK OPERATIONS GMBH (DE) 2026-03-12 US disclosed
EP-4448702-B1 HYDRAULIC LUBRICANT FORMULATIONS WITH HIGH FLASH POINT AND IMPROVED SHEAR STABILITY EVONIK OPERATIONS GMBH (DE) 2026-02-04 EP disclosed
US-20260015536-A1 METHOD OF COOLING AN ELECTRICAL EQUIPMENT SYSTEM BY USING A DIELECTRIC FLUID COMPOSITION HAVING GOOD HEAT DISSIPATION OVER A WIDE TEMPERATURE RANGE EVONIK OPERATIONS GMBH (DE) 2026-01-15 US disclosed
WO-1995027022-A1 LUBRICATION OIL COMPOSITION EXXON RESEARCH & ENGINEERING COMPANY (US) 1995-10-12 WO disclosed
EP-0191967-B1 REACTION PRODUCTS OF ALKENYLSUCCINIC COMPOUNDS WITH AROMATIC AMINES AND LUBRICANT COMPOSITIONS THEREOF MOBIL OIL CORPORATION (US) 1992-03-04 EP disclosed
US-4895579-A DISPERSANT, ANTIOXIDANT MOBIL OIL CORPORATION (US) 1990-01-23 US disclosed
US-4803004-A DISPERSANTS, OXIDATION RESISTANCE MOBIL OIL CORPORATION (US) 1989-02-07 US disclosed
US-4698169-A DISPERSANT, ANTIOXIDANT OIL ADDITIVES MOBIL OIL CORPORATION (US) 1987-10-06 US disclosed
EP-0191967-A2 Reaction products of alkenylsuccinic compounds with aromatic amines and lubricant compositions thereof MOBIL OIL CORPORATION (US) 1986-08-27 EP disclosed
US-4394279-A Antioxidant combinations of sulfur containing molybdenum complexes and aromatic amine compounds for lubricating oils CHEVRON RESEARCH COMPANY (US) 1983-07-19 US disclosed
US-4370246-A Antioxidant combinations of molybdenum complexes and aromatic amine compounds CHEVRON RESEARCH COMPANY (US) 1983-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606729-B2 Use of polymeric-inorganic nanoparticle compositions as heat transfer fluids in battery or other electrical equipment systems ADH1A, MMAB, ACR SIGMAR1 3199/4885HTR1B 2830/4885ALDH1A1 73/4885
US-20260071133-A1 HYDRAULIC LUBRICANT FORMULATIONS WITH HIGH FLASH POINT AND IMPROVED SHEAR STABILITY F5, FGB, MST1 SIGMAR1 764/4885HTR1B 527/4885ALDH1A1 3064/4885
US-20260015536-A1 METHOD OF COOLING AN ELECTRICAL EQUIPMENT SYSTEM BY USING A DIELECTRIC FLUID COMPOSITION HAVING GOOD HEAT DISSIPATION OVER A WIDE TEMPERATURE RANGE SLC5A11, HCN3, SCN11A SIGMAR1 2628/4885HTR1B 1081/4885ALDH1A1 3477/4885
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT RAF1, PFKP, TP53RK SIGMAR1 4678/4885HTR1B 3206/4885ALDH1A1 3108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.