Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | TEK | Q02763 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542905 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL7544894 | 0.85 | KDR (0.40) | RAB9AKMT2AMEN1KDR | |
| SCHEMBL7551347 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL8666294 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL7548776 | 0.80 | MAPT (0.46) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL7544185 | 0.78 | MAPT (0.49) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL7543927 | 0.78 | MAPT (0.56) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL7542952 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL7549421 | 0.77 | MAPK13 (0.41) | RAB9AMAPTGAAPOLBKDR | |
| SCHEMBL7542964 | 0.77 | MAPT (0.56) | SMN1; SMN2NPC1RAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |