Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307504 | 0.79 | THRB (0.44) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL9274200 | 0.79 | THRB (0.44) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL7536676 | 0.79 | THRB (0.44) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL31489866 | 0.78 | NAAA (0.41) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL113024 | 0.77 | CYP19A1 (0.42) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL547983 | 0.76 | NAAA (0.44) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL43550 | 0.76 | NAAA (0.41) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL548469 | 0.76 | NPSR1 (0.41) | NAAANPSR1CYP19A1THRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL27804949 | 0.75 | EPHX1 (0.41) | NAAACA2NPSR1CYP19A1THRB | |
| SCHEMBL1615681 | 0.74 | NAAA (0.40) | NAAACA2NPSR1CYP19A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261731-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | Urtti, Arto (FI) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001062946-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | URTTI ARTO (FI) | 2001-08-30 | — | — | WO | disclosed |