Fenpiprane

Fenpiprane

SCHEMBL24507

c1ccc(C(CCN2CCCCC2)c2ccccc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.66
KCNA3 P22001 1/20 0.64
CCR2 P41597 4/20 0.60
CYP2D6 P10635 1/20 0.59
OPRL1 P41146 1/20 0.58
SIGMAR1 Q99720 1/20 0.55
CACNA1B Q00975 1/20 0.52
SLC6A3 Q01959 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prozapine SCHEMBL25765 1.00 ALDH1A1 (0.66) ALDH1A1KCNA3CCR2CYP2D6OPRL1
Fenpiprane SCHEMBL11585426 0.98 ALDH1A1 (0.64) ALDH1A1KCNA3CCR2CYP2D6OPRL1
Prozapine SCHEMBL365642 0.98 ALDH1A1 (0.64) ALDH1A1KCNA3CCR2CYP2D6OPRL1
SCHEMBL67164 0.89 SIGMAR1 (0.66) ALDH1A1SIGMAR1CACNA1B
Hydrochloric Acid SCHEMBL29267226 0.88 CYP3A4 (0.66) ALDH1A1KCNA3CCR2CYP2D6OPRL1
Hydrochloric Acid SCHEMBL30517299 0.88 CYP3A4 (0.66) ALDH1A1KCNA3CCR2CYP2D6OPRL1
Diisopromine SCHEMBL28142824 0.84 ALDH1A1 (0.51) ALDH1A1KCNA3CCR2CYP2D6OPRL1
SCHEMBL5757757 0.83 ALDH1A1 (0.53) ALDH1A1KCNA3CCR2CYP2D6SIGMAR1
SCHEMBL7547846 0.83 HTR1A (0.61) SLC6A3
SCHEMBL6009479 0.83 ALDH1A1 (0.53) ALDH1A1KCNA3CCR2CYP2D6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11065205-B2 Immediate/delayed drug delivery DRUG DELIVERY INTERNATIONAL LIMITED (GB) 2021-07-20 US claimed
WO-2019155389-A1 AN AQUEOUS MUCOADHESIVE AND BIOADHESIVE COMPOSITION FOR THE TREATMENT TARGET ONCOLOGY INC. (US) 2019-08-15 WO claimed
US-20190125679-A1 IMMEDIATE/DELAYED DRUG DELIVERY UNIVERSITY OF STRATHCLYDE (GB) 2019-05-02 US claimed
EP-3373943-A1 CONTROL OF CELLULAR REDOX LEVELS Mckenna, Elizabeth (US) 2018-09-19 EP claimed
CN-108430482-A Control of cellular redox levels 伊丽莎白·麦克纳 2018-08-21 CN claimed
EP-2956450-B1 HYDROXYINDALPINE DERIVATIVES AND THEIR MEDICAL USE UNIV MUENCHEN TECH (DE) 2018-07-25 EP claimed
EP-2542226-B1 DELAYED PROLONGED DRUG DELIVERY UNIV STRATHCLYDE (GB) 2017-11-22 EP claimed
WO-2017083470-A1 CONTROL OF CELLULAR REDOX LEVELS MCKENNA ELIZABETH (US) 2017-05-18 WO claimed
US-9474719-B2 Pulsatile drug release UNIVERSITY OF STRATHCLYDE (GB) 2016-10-25 US claimed
US-9283192-B2 Delayed prolonged drug delivery UNIVERSITY OF STRATHCLYDE (GB) 2016-03-15 US claimed
CN-1738599-A Mucoadhesive erodible drug delivery device for controlled drug administration with other active compounds ACCESS PHARMA INC (US) 2006-02-22 CN claimed
EP-1418889-A2 MUCOADHESIVE ERODIBLE DRUG DELIVERY DEVICE FOR CONTROLLED ADMINISTRATION OF PHARMACEUTICALS AND OTHER ACTIVE COMPOUNDS Access Pharmaceuticals, Inc. (US) 2004-05-19 EP claimed
US-20030138490-A1 Synthesis and uses of polymer gel nanoparticle networks HU ZHIBING (US) 2003-07-24 US claimed
US-6585997-B2 Comprising a first, water-soluble adhesive layer to be placed in contact with a mucosal surface and a second, water-erodible non- adhesive backing layer that controls residence time of the device ACCESS PHARMACEUTICALS, INC. 2003-07-01 US claimed
WO-2003022910-A1 SYNTHESIS AND USES OF POLYMER GEL NANOPARTICLE NETWORKS ACCESS PHARMACEUTICALS, INC. (US) 2003-03-20 WO claimed
US-20030044446-A1 Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds MUCOADHESIVE ERODIBLE DRUG DELIVERY DEVICE FOR CONTROLLED ADMN. OF PHARMACEUTICALS & OTHER ACTI 2003-03-06 US claimed
WO-2003015748-A2 MUCOADHESIVE ERODIBLE DRUG DELIVERY DEVICE FOR CONTROLLED ADMINISTRATION OF PHARMACEUTICALS AND OTHER ACTIVE COMPOUNDS ACCESS PHARMACEUTICALS, INC. (US) 2003-02-27 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138490-A1 Synthesis and uses of polymer gel nanoparticle networks NCLN, PNN, TAGLN2 ALDH1A1 2310/4885KCNA3 3459/4885CCR2 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.