Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20520335 | 0.91 | NAPRT (0.47) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL7551785 | 0.87 | KDM4E (0.40) | NAPRTKDM4CKDM4EKMT2ATP53 | |
| Chlorobenzene SCHEMBL8805059 | 0.87 | NAPRT (0.42) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL28101555 | 0.80 | NAPRT (0.41) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL19857454 | 0.78 | NAPRT (0.57) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL7553608 | 0.78 | NAPRT (0.46) | NAPRTKDM4CPRKCIKMT2AAKR1C3 | |
| SCHEMBL20520322 | 0.77 | NAPRT (0.52) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL8798744 | 0.76 | NAPRT (0.44) | NAPRTKDM4CKDM4EKMT2AHSD17B10 | |
| SCHEMBL7547531 | 0.75 | NAPRT (0.44) | NAPRTKDM4CPRKCIKDM4EKMT2A | |
| SCHEMBL7548771 | 0.74 | BCAT2 (0.46) | NAPRTKDM4CPRKCIKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |