Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | P4HB | P07237 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106759 | 0.85 | XDH (0.62) | MAOAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL29391027 | 0.85 | XDH (0.62) | MAOAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL28106334 | 0.83 | XDH (0.60) | MAOAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL433900 | 0.83 | EGFR (0.71) | CYP3A4MAPTCYP1A1CYP1A2ABCB1 | |
| SCHEMBL28106758 | 0.81 | MEN1 (0.67) | MAOAMEN1CYP3A4MAPTKMT2A | |
| Izalpinin SCHEMBL7551775 | 0.81 | MAOA (0.83) | MAOAMEN1CYP3A4MAPTKMT2A | |
| Izalpinin SCHEMBL29974286 | 0.81 | MAOA (0.83) | MAOAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL16823312 | 0.80 | EGFR (0.70) | MAPTABCB1BCHEACHESIGMAR1 | |
| SCHEMBL119434 | 0.79 | MEN1 (0.64) | MAOAMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL431393 | 0.79 | EGFR (0.69) | BCHEACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214308-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021608-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2001-03-29 | — | — | WO | disclosed |