SCHEMBL7548622

SCHEMBL7548622

Cn1c(-c2ccc(Cl)cc2)c(C#N)c(Br)c1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.39
ALDH1A1 P00352 7/20 0.39
LMNA P02545 6/20 0.39
HPGD P15428 4/20 0.39
GAA P10253 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HTT P42858 3/20 0.39
GLA P06280 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
GRIA2 P42262 1/20 0.38
GRIA4 P48058 1/20 0.38
CYP11B2 P19099 2/20 0.36
CYP11B1 P15538 1/20 0.36
MAOA P21397 1/20 0.36
AR P10275 2/20 0.35
NPSR1 Q6W5P4 2/20 0.33
POLB P06746 2/20 0.33
NTRK1 P04629 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL27614926 0.89 GRIA2 (0.38) KDM4EALDH1A1LMNAGAAKMT2A
SCHEMBL8976138 0.86 ALDH1A1 (0.41) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL8994449 0.83 KDM4E (0.39) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL9217692 0.82 ALDH1A1 (0.38) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL7508068 0.81 KDM4E (0.37) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL7499361 0.81 KDM4E (0.37) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL9519227 0.81 GRIA2 (0.42) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL9423599 0.81 KDM4E (0.38) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL9057679 0.80 HTT (0.36) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL5819212 0.80 KDM4E (0.34) KDM4EALDH1A1LMNAHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111253821-B High-solid-content copper-free linear self-polishing marine antifouling paint 浙江省海洋开发研究院 2022-03-22 CN claimed
CN-111253821-A High-solid-content copper-free linear self-polishing marine antifouling paint 浙江省海洋开发研究院 2020-06-09 CN claimed
EP-0594942-B1 N-aminoalkylcarbonyloxyalkylpyrrole insecticidal acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-09-04 EP claimed
EP-0594940-B1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0594940-A1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed
US-5286741-A N-oxy- and thioalkylcarbonyloxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-02-15 US claimed
CN-115850646-B Waterborne polyurethane for marine antifouling and preparation method thereof 嘉兴学院 2024-01-26 CN disclosed
CN-115850646-A Waterborne polyurethane for marine antifouling and preparation method thereof 嘉兴学院 2023-03-28 CN disclosed
CN-111253821-B High-solid-content copper-free linear self-polishing marine antifouling paint 浙江省海洋开发研究院 2022-03-22 CN disclosed
CN-109006823-B Application of 2-aryl substituted pyrrole compound in oncomelania killing drug 江苏省血吸虫病防治研究所 2021-05-07 CN disclosed
CN-109169668-B Application of 2-aryl substituted pyrrole compound in drug for killing vesicular snails 江苏省血吸虫病防治研究所 2021-05-07 CN disclosed
CN-109006824-B Application of 2-aryl substituted pyrrole compound in medicament for killing amphioxus 江苏省血吸虫病防治研究所 2021-04-27 CN disclosed
US-5625082-A 2-aryl-5-(trifluoromethyl)-2-pyrroline compounds useful in the manufacture of insecticidal, nematocidal and acaricidal arylpyrroles AMERICAN HOME PRODUCTS CORPORATION (US) 1997-04-29 US disclosed
US-5563279-A Debrominative chlorination of pyrroles AMERICAN CYANAMID COMPANY (US) 1996-10-08 US disclosed
US-5449789-A Debrominative chlorination of pyrroles AMERICAN CYANAMID COMPANY (US) 1995-09-12 US disclosed
US-5380876-A 2-aryl-5(trifluoromethyl)-2-pyrroline compounds useful in the manufacture of insecticidal, nematocidal and acaricidal arylpyrroles AMERICAN CYANAMID COMPANY (US) 1995-01-10 US disclosed
EP-0600157-A1 Debrominative chlorination of pyrroles AMERICAN CYANAMID COMPANY (US) 1994-06-08 EP disclosed
US-5128485-A SYNTHESIS OF 2-ARYL-5-(TRIFLUOROMETHYL)PYRROLES USEFUL AS PESTICIDAL AGENTS AND AS INTERMEDIATES FOR THE PREPARATION OF SAID AGENTS AMERICAN CYANAMID COMPANY (US) 1992-07-07 US disclosed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP disclosed