Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544358 | 0.91 | AGPAT2 (0.52) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7548150 | 0.87 | MEN1 (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7545416 | 0.87 | RORC (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7544449 | 0.84 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7547340 | 0.82 | MEN1 (0.60) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL14776973 | 0.79 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7545585 | 0.79 | MAPK13 (0.46) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7545139 | 0.79 | AGPAT2 (0.53) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7544713 | 0.78 | AGPAT2 (0.60) | KMT2APOLBMAPTTP53 | |
| SCHEMBL7548721 | 0.77 | EPHX2 (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |