SCHEMBL7547340

SCHEMBL7547340

CC(=O)Nc1ccc(OCc2nc3ccccc3o2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.60
KMT2A Q03164 6/20 0.60
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
PDE10A Q9Y233 1/20 0.52
MAPT P10636 3/20 0.52
POLB P06746 2/20 0.52
GAA P10253 1/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
HTT P42858 1/20 0.50
LMNA P02545 2/20 0.49
CYP1A2 P05177 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7542952 0.89 SMN1; SMN2 (0.57) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL11033217 0.84 PDE10A (0.52) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7542425 0.83 ALOX5 (0.48) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7548150 0.82 MEN1 (0.50) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL7545585 0.82 MAPK13 (0.46) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7545416 0.82 RORC (0.55) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL7545090 0.82 MAPT (0.52) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7548632 0.82 NPC1 (0.49) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7544987 0.82 MAPT (0.56) MEN1KMT2ANPC1RAB9APDE10A
SCHEMBL7548682 0.82 RAB9A (0.52) MEN1KMT2ANPC1RAB9APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed