SCHEMBL7548711

SCHEMBL7548711

CCOC(=O)n1c(=O)cc[nH]c1=S

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.38
LMNA P02545 2/20 0.38
LPO P22079 2/20 0.38
CYP1A2 P05177 2/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TP53 P04637 1/20 0.37
KMT2A Q03164 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.35
PPARG P37231 1/20 0.35
RAB9A P51151 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11582763 0.80 SIGMAR1 (0.36) LMNALPOALDH1A1KMT2AMEN1
SCHEMBL11465763 0.72 BCHE (0.43) LMNACYP1A2ALDH1A1L3MBTL1TP53
SCHEMBL26295022 0.71 LPO (0.57) LMNALPOCYP1A2ALDH1A1KDM4E
SCHEMBL10990597 0.70 HPGD (0.48) LMNALPOCYP1A2ALDH1A1KDM4E
SCHEMBL30099704 0.70 P2RX4 (0.42) LMNAALDH1A1KDM4EHPGDKMT2A
SCHEMBL28545719 0.69 ALDH1A1 (0.50) LMNACYP1A2ALDH1A1KDM4EHPGD
SCHEMBL8656963 0.68 ALDH1A1 (0.45) LMNALPOCYP1A2ALDH1A1KDM4E
SCHEMBL24205120 0.68 POLB (0.42) TDP1HTT
SCHEMBL1526613 0.67 ELANE (0.37) NUDT1LMNAALDH1A1KDM4EHPGD
SCHEMBL27797893 0.67 ALDH1A1 (0.34) LMNAALDH1A1KDM4EHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11092461-A None JP disclosed
EP-0896043-B1 Adhesive TOKUYAMA CORP (JP) 2002-10-23 EP disclosed
EP-0802194-B1 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORP (JP) 2002-06-19 EP disclosed
US-6133338-A TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF TOKUYAMA CORPORATION (JP) 2000-10-17 US disclosed
JP-H1192461-A DISULFIDE COMPOUND AND METAL SURFACE TREATING AGENT TOKUYAMA CORP 1999-04-06 JP disclosed
EP-0896043-A1 Adhesive TOKUYAMA CORPORATION (JP) 1999-02-10 EP disclosed
US-5795497-A Thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1998-08-18 US disclosed
EP-0802194-A2 Novel thiouracil derivatives and metal surface-treating agent comprising thereof TOKUYAMA CORPORATION (JP) 1997-10-22 EP disclosed