SCHEMBL7548857

SCHEMBL7548857

CC(=O)Nc1ccc(OCc2nc3ccccc3o2)cc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.44
RAB9A P51151 5/20 0.42
ALOX5AP P20292 1/20 0.42
PIK3CA P42336 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
NPC1 O15118 3/20 0.39
ALOX5 P09917 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
LMNA P02545 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541593 0.91 PDE10A (0.43) PDE10ARAB9AALOX5APMEN1KMT2A
SCHEMBL7545585 0.87 MAPK13 (0.46) PDE10ARAB9AALOX5APMEN1KMT2A
SCHEMBL7542425 0.85 ALOX5 (0.48) PDE10ARAB9AALOX5APMEN1KMT2A
SCHEMBL7548682 0.85 RAB9A (0.52) PDE10ARAB9AALOX5APMEN1KMT2A
SCHEMBL7547292 0.84 MAPT (0.52) PDE10ARAB9AMEN1KMT2ANPC1
SCHEMBL7544961 0.81 RAB9A (0.47) PDE10ARAB9AMEN1KMT2ANPC1
SCHEMBL7547340 0.80 MEN1 (0.60) PDE10ARAB9AMEN1KMT2ANPC1
SCHEMBL7541056 0.78 CETP (0.44) MAOBALOX5TSHRS1PR1
SCHEMBL7547297 0.78 ALOX5 (0.59) RAB9AALOX5APMEN1KMT2ANPC1
SCHEMBL7541142 0.78 PDE10A (0.45) PDE10ARAB9AALOX5APMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed