Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551128 | 0.95 | AAK1 (0.33) | AAK1 | |
| SCHEMBL7550867 | 0.92 | AAK1 (0.32) | AAK1 | |
| SCHEMBL7547793 | 0.88 | AAK1 (0.35) | AAK1 | |
| SCHEMBL7554010 | 0.88 | AAK1 (0.36) | AAK1 | |
| SCHEMBL7554390 | 0.88 | — | — | |
| SCHEMBL7550465 | 0.85 | MAPK14 (0.31) | — | |
| SCHEMBL7547271 | 0.82 | RORC (0.31) | — | |
| SCHEMBL7555176 | 0.82 | KDM4E (0.31) | — | |
| SCHEMBL7548644 | 0.80 | MAPK14 (0.32) | AAK1 | |
| SCHEMBL7549047 | 0.80 | MAPK14 (0.33) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657427-B1 | Tricyclic indole-2-carboxylic acid derivatives being selective antagonists of the NMDA receptor | SUMITOMO PHARMA (JP) | 2002-06-19 | — | — | EP | disclosed |
| EP-0657427-A1 | Tricyclic indole-2-carboxylic acid derivatives being selective antagonists of the NMDA receptor | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-06-14 | — | — | EP | disclosed |