SCHEMBL7548989

SCHEMBL7548989

CCCc1cccc(Oc2ccccc2O)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.51
PTGS2 P35354 1/20 0.51
IAPP P10997 4/20 0.44
ELANE P08246 2/20 0.42
CTSG P08311 1/20 0.42
TP53 P04637 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 2/20 0.40
ALOX15 P16050 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTR1A P08908 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9445272 0.91 ALOX5 (0.59) ALOX5PTGS2IAPPELANECTSG
SCHEMBL983635 0.88 SLC6A2 (0.47) TP53CA1CA2TSHRLMNA
SCHEMBL982656 0.87 LTB4R (0.44) ALOX5PTGS2TP53CA1CA2
SCHEMBL6719931 0.85 ALOX5 (0.62) ALOX5PTGS2ELANECTSGTP53
SCHEMBL6723731 0.82 ALOX5 (0.46) ALOX5PTGS2IAPPTP53CA1
SCHEMBL984080 0.82 CTSL (0.41) ELANECTSGTP53CA1CA2
SCHEMBL6722882 0.80 ALOX5 (0.43) ALOX5PTGS2ELANECA1CA2
SCHEMBL23748452 0.79 ALOX5 (0.77) ALOX5PTGS2ELANECTSGTP53
SCHEMBL1840411 0.79 SLC6A2 (0.43) ALOX5PTGS2IAPPLMNAALOX15
SCHEMBL1838446 0.79 CA1 (0.40) TP53CA1CA2TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed