Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938245 | 0.84 | CES2 (0.42) | CA12CA1CA9IDO1CES2 | |
| SCHEMBL27786798 | 0.80 | — | — | |
| SCHEMBL4929798 | 0.80 | GAA (0.41) | CA12CA1CA9CYP3A4GAA | |
| SCHEMBL18302718 | 0.80 | GAA (0.32) | GAAAHR | |
| SCHEMBL13550169 | 0.80 | RAPGEF4 (0.34) | CYP3A4 | |
| SCHEMBL30543313 | 0.80 | GAA (0.32) | GAAAHR | |
| SCHEMBL29472174 | 0.79 | ALDH1A1 (0.53) | CA12CA1CA9IDO1CYP3A4 | |
| SCHEMBL3682577 | 0.79 | ALDH1A1 (0.53) | CA1CA9CYP3A4CES1MAPK1 | |
| SCHEMBL6741646 | 0.78 | RAPGEF4 (0.33) | CYP3A4 | |
| Methyl Alcohol SCHEMBL28266439 | 0.78 | CES2 (0.43) | CA12CA1CA9IDO1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838242-B1 | Thermally responsive frangible bulb | TYCO FIRE PRODUCTS MFG LTD (GB) | 2002-06-05 | — | — | EP | disclosed |
| US-5967238-A | USED TO AUTOMATICALLY RELEASE QUICK RESPONSE, FIRE PROTECTION SPRINKLERS, LIQUID EXPANDS TO FILL AND FRACTURE THE BULB WHEN HEATED, HALOGEN DERIVATIVE OF AN AROMATIC HYDROCARBON CONTAINING TWO OR MORE HALOGEN SUBSTITUENTS, AN ALIPHATIC | GRINNELL MANUFACTURING (UK) LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |
| EP-0838242-A2 | Thermally responsive frangible bulb | Grinnell Manufacturing (UK) Limited (GB) | 1998-04-29 | — | — | EP | disclosed |