Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544065 | 0.95 | ITGB1 (0.47) | ACEITGB1ITGA4FPR2MMP2 | |
| SCHEMBL7545886 | 0.93 | ITGB1 (0.47) | ACEITGB1ITGA4FPR2MMP2 | |
| SCHEMBL7539243 | 0.92 | CNR2 (0.45) | ACEITGB1ITGA4FPR2MMP2 | |
| SCHEMBL7539503 | 0.91 | FPR2 (0.56) | ITGB1ITGA4FPR2MMP3 | |
| SCHEMBL7543424 | 0.89 | ITGB1 (0.43) | ACEITGB1ITGA4FOLH1FPR2 | |
| SCHEMBL7543419 | 0.89 | ITGB1 (0.43) | ACEITGB1ITGA4FOLH1FPR2 | |
| SCHEMBL7538904 | 0.89 | MEN1 (0.48) | ITGB1ITGA4FPR2MMP2 | |
| SCHEMBL7541819 | 0.88 | ACE (0.41) | ACEFOLH1FPR2MMP2MMP7 | |
| SCHEMBL7545871 | 0.88 | RNASEL (0.43) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7545897 | 0.84 | ITGB1 (0.45) | ITGB1ITGA4FPR2MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |