Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544065 | 0.91 | ITGB1 (0.47) | ITGB1ITGA4MMP2FPR2 | |
| SCHEMBL7544716 | 0.90 | MEN1 (0.46) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7544720 | 0.90 | MEN1 (0.46) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7546030 | 0.89 | MEN1 (0.42) | MEN1KMT2AMAPTNPSR1MYOC | |
| SCHEMBL7545886 | 0.89 | ITGB1 (0.47) | MAPTITGB1ITGA4SMN1; SMN2MMP2 | |
| SCHEMBL7549214 | 0.89 | ACE (0.46) | ITGB1ITGA4MMP2FPR2 | |
| SCHEMBL7539243 | 0.88 | CNR2 (0.45) | KMT2AITGB1ITGA4MMP2PSMB1 | |
| SCHEMBL7539503 | 0.87 | FPR2 (0.56) | MAPTMMP1ITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL7541665 | 0.85 | MEN1 (0.46) | MEN1KMT2AMMP1FCER2ITGB1 | |
| SCHEMBL7545871 | 0.84 | RNASEL (0.43) | MMP1MMP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |