Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484239 | 1.00 | RET (0.45) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL15665353 | 1.00 | RET (0.45) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL15665354 | 1.00 | RET (0.45) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL9793694 | 0.85 | RET (0.36) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL9793697 | 0.85 | RET (0.36) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL9426196 | 0.78 | RET (0.49) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL30231793 | 0.76 | MAPK14 (0.46) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL1788714 | 0.76 | RET (0.51) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL1786883 | 0.76 | RET (0.51) | RETMAPK14CAMK1DHDAC6TBXA2R | |
| SCHEMBL3708800 | 0.76 | RET (0.51) | RETMAPK14CAMK1DHDAC6TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746552-B1 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN SA (CH) | 2002-06-12 | — | — | EP | disclosed |
| US-5665696-A | ODORANT COMPOSITIONS | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1997-09-09 | — | — | US | disclosed |
| EP-0746552-A1 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-12-11 | — | — | EP | disclosed |
| WO-1996020185-A2 | TETRAHYDROFURANS AND TETRAHYDROPYRANS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1996-07-04 | — | — | WO | disclosed |
| US-4605793-A | REACTING ALPHA OR BETA PINENE WITH CARBON MONOXIDE AND HYDROGEN; REACTING ALDEHYDE FORMED WITH METHYL ETHYL KETONE; REDUCTION | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4591451-A | Methyl substituted pinyl oxopentenes and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1986-05-27 | — | — | US | disclosed |
| US-4549971-A | Methyl substituted pinyl oxopentenes, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1985-10-29 | — | — | US | disclosed |
| US-4533491-A | Organoleptic use of methyl substituted pinyl oxopentenes | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1985-08-06 | — | — | US | disclosed |
| US-4510340-A | PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1985-04-09 | — | — | US | disclosed |
| US-4506104-A | FERFUMES; FLAVORS, FOODS | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4481221-A | NORPINANE OR NORBORNANE RING | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-11-06 | — | — | US | disclosed |
| US-4428387-A | Use of methyl substituted pinyl oxopentenes, for augmenting, enhancing of modifying the aroma or taste of smoking tobacco and smoking tobacco articles | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4425365-A | HYDROFORMYLATION OF PINENE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-01-10 | — | — | US | disclosed |
| US-4424378-A | Methyl substituted pinyl oxopentenes, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0011272-B1 | PROCESS FOR THE PREPARATION OF ALDEHYDES AND USE OF THE REACTION PRODUCTS AS PERFUMES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4334100-A | Production of aldehydes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1982-06-08 | — | — | US | disclosed |
| EP-0018504-A1 | Use of aldehydes as microbicides | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0011272-A2 | Process for the preparation of aldehydes and use of the reaction products as perfumes | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-05-28 | — | — | EP | disclosed |
| US-4125484-A | Tertiary alcohols | SHELL OIL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |