SCHEMBL9793697

SCHEMBL9793697

CC1(C)C2CCC1C(CC=O)C2

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.36
MAPK14 Q16539 1/20 0.36
CAMK1D Q8IU85 1/20 0.36
HDAC6 Q9UBN7 2/20 0.33
TBXA2R P21731 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793694 1.00 RET (0.36) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL14484239 0.85 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL15665354 0.85 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL15665353 0.85 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL7549733 0.85 RET (0.45) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL11602001 0.77 RET (0.42) RETMAPK14CAMK1DHDAC6TBXA2R
SCHEMBL11603418 0.76 RET (0.41) RETMAPK14CAMK1DHDAC6
SCHEMBL6202519 0.74 RET (0.35) RETMAPK14CAMK1DHDAC6
SCHEMBL11604019 0.70 RET (0.40) RETMAPK14CAMK1DHDAC6
SCHEMBL4623135 0.69 ALDH1A1 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3083936-A None JP disclosed
JP-H0383936-A 77-DIMETHYL NORBORNANE DERIVATIVE COCA COLA CO:THE 1991-04-09 JP disclosed