Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 9/20 | 0.50 |
| ▸ | MAX | P61244 | 5/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20721738 | 0.96 | GSTM2 (0.51) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL13525106 | 0.91 | MEN1 (0.52) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL13525111 | 0.89 | MEN1 (0.50) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL11036403 | 0.89 | MYC (0.50) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL13484057 | 0.85 | GSTM2 (0.47) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL29455613 | 0.83 | MEN1 (0.50) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL7059267 | 0.80 | HCAR3 (0.43) | HTTPOLBGAAMAPT | |
| SCHEMBL13252231 | 0.79 | MEN1 (0.56) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL13660289 | 0.79 | MEN1 (0.42) | MYCMAXGSTM2MEN1KMT2A | |
| SCHEMBL4355207 | 0.77 | KMT2A (0.48) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119554-A4 | XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE | TROPIX INC (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1119554-A1 | XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE | TROPIX, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000015618-A1 | XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE | TROPIX, INC. (US) | 2000-03-23 | — | — | WO | disclosed |
| US-RE36536-E | ENZYME CLEAVES THE ENZYME-CLEAVABLE GROUP TO FORM A NEGATIVELY CHARGED SUBSTITUENT BONDED TO THE DIOXETANE, WHICH CAUSES THE DIOXETANE TO DECOMPOSE TO FORM LUMINESCENT SUBSTANCE, MEASURING THE INTENSITY GIVES CONCENTRATION | TROPIX. INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0435998-B1 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES | TROPIX INC (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0907082-A2 | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes | TROPIX, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0859062-A2 | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes | TROPIX, INC. (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5605795-A | Assays using chemiluminescent, enzymatically cleavable substituted 1,2-dioxetanes and kits therefor | TROPIX, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5220005-A | Reactable with enzyme to release optically detectable energy | TROPIX, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0435998-A4 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0435998-A1 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES | TROPIX, INC. (US) | 1991-07-10 | — | — | EP | disclosed |
| WO-1991001492-A1 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES | TROPIX, INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4978614-A | RELEASING LIGHT ENERGY; LUMINESCENCE | TROPIX, INC. (US) | 1990-12-18 | — | — | US | disclosed |