SCHEMBL7550100

SCHEMBL7550100

CCOC(Cc1cnc2ccc(OCc3ccc(Cl)cc3)cc2c1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.60
PPARG P37231 11/20 0.53
PPARD Q03181 5/20 0.53
FFAR1 O14842 1/20 0.47
PTPN1 P18031 1/20 0.47
MAOB P27338 2/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7551490 0.92 PPARA (0.60) PPARAPPARGPPARDFFAR1PTPN1
SCHEMBL7548625 0.87 PPARA (0.55) PPARAPPARGPPARDFFAR1MAOB
SCHEMBL7556358 0.82 PTPN1 (0.47) PPARAPPARGPPARDPTPN1MAOB
SCHEMBL7070013 0.81 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL7551266 0.78 MAOB (0.58) PPARAPPARGPPARDMAOBMAOA
SCHEMBL7556111 0.78 PPARG (0.58) PPARAPPARGPTPN1MAOB
SCHEMBL7549067 0.77 MAOB (0.47) PPARAPPARGPPARDPTPN1MAOB
SCHEMBL7069280 0.77 PPARG (0.54) PPARAPPARGPPARDMAOB
SCHEMBL7070373 0.76 PPARA (0.67) PPARAPPARGPPARD
SCHEMBL7551042 0.75 PPARA (0.40) PPARAPPARGPPARDFFAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032330-A1 Propionic acid derivatives NOMURA YUTAKA (JP) 2002-03-14 US disclosed
EP-0994095-A1 PROPIONIC ACID DERIVATIVES NIPPON CHEMIPHAR CO., LTD. (JP) 2000-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032330-A1 Propionic acid derivatives ABAT, ACAT1, PDXK PPARA 56/4885PPARG 123/4885PPARD 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.