Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548625 | 0.90 | PPARA (0.55) | MAOBITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7551266 | 0.82 | MAOB (0.58) | MAOBITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7556358 | 0.80 | PTPN1 (0.47) | MAOBPPARAMAOAPPARGPPARD | |
| SCHEMBL7550100 | 0.77 | PPARA (0.60) | MAOBPPARAMAOAPPARGPPARD | |
| SCHEMBL7069695 | 0.70 | PPARA (0.55) | MAOBPPARAPPARGPPARD | |
| SCHEMBL27994380 | 0.70 | ALDH1A1 (0.57) | MAOBMAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7551490 | 0.69 | PPARA (0.60) | MAOBPPARAMAOAPPARGPPARD | |
| SCHEMBL20377564 | 0.68 | MAOB (0.76) | MAOBITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7070013 | 0.68 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL7067696 | 0.67 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032330-A1 | Propionic acid derivatives | NOMURA YUTAKA (JP) | 2002-03-14 | — | — | US | disclosed |
| EP-0994095-A1 | PROPIONIC ACID DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032330-A1 | Propionic acid derivatives | ABAT, ACAT1, PDXK | MAOB 1256/4885ITGB3 2584/4885ITGA2B 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.