Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 7/20 | 0.33 |
| ▸ | RARA | P10276 | 6/20 | 0.33 |
| ▸ | RARG | P13631 | 5/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737372 | 0.78 | AKR1B1 (0.42) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL22426598 | 0.69 | RARB (0.67) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL8329088 | 0.69 | MAPT (0.52) | — | |
| SCHEMBL20636850 | 0.69 | AKR1B1 (0.37) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL5737881 | 0.68 | AKR1B1 (0.39) | RARBRARARARGCYP26A1CYP3A4 | |
| SCHEMBL20556232 | 0.66 | HNF4A (0.62) | FFAR1FFAR4HAO1 | |
| SCHEMBL9526910 | 0.66 | RARB (0.37) | RARBRARARARGCYP26A1CYP3A4 | |
| SCHEMBL2837861 | 0.66 | RARB (0.45) | RXRARXRBRXRGRARBRARA | |
| SCHEMBL31064115 | 0.66 | HNF4A (0.38) | RARBRARARARGFFAR1FFAR4 | |
| SCHEMBL6592227 | 0.65 | RARB (0.46) | RXRARARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN, INC. | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | RARA, RARB, RARG | RXRA 7/4885RXRB 13/4885RXRG 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.