Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620412 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TNFRIPK1RAPGEF4HTR2A | |
| SCHEMBL13755137 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TNFRIPK1RAPGEF4CES1 | |
| SCHEMBL4812657 | 0.83 | HTR2A (0.39) | TNFRIPK1RAPGEF4HTR2AHTR2C | |
| SCHEMBL29449511 | 0.81 | ALDH1A1 (0.37) | ALDH1A1RAPGEF4CES1TP53MEN1 | |
| SCHEMBL13905953 | 0.81 | ACHE (0.38) | TNFRIPK1RAPGEF4HTR2AHTR2C | |
| SCHEMBL15497514 | 0.81 | ALDH1A1 (0.37) | ALDH1A1RAPGEF4CES1TP53MEN1 | |
| SCHEMBL180373 | 0.79 | HTR2A (0.36) | ALDH1A1TNFRIPK1RAPGEF4HTR2A | |
| SCHEMBL900037 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HTR2AHTR2CHTR2BCES1 | |
| SCHEMBL15611127 | 0.75 | TRPA1 (0.41) | ALDH1A1TNFRIPK1MEN1LMNA | |
| SCHEMBL21996002 | 0.75 | TNF (0.33) | TNFRIPK1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872476-B1 | Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds | BAYER AG (DE) | 2002-07-03 | — | — | EP | claimed |
| EP-0872476-A2 | Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds | BAYER AG (DE) | 1998-10-21 | — | — | EP | claimed |
| US-5824817-A | Herbicidal compositions based on 2,6-dichloro-3-fluoro-benzonitrile, and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | claimed |
| EP-0657407-B1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1997-12-10 | — | — | EP | claimed |
| US-5670694-A | AMMOXIDATION OF CORRESPONDING TOLUENE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0731087-A1 | Process for the preparation of 2,4-dichloro-5-fluorobenzonitrile and 2,6-dichloro-3-fluorobenzonitrile | BAYER AG (DE) | 1996-09-11 | — | — | EP | claimed |
| EP-0713862-A2 | Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds | BAYER AG (DE) | 1996-05-29 | — | — | EP | claimed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | claimed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | claimed |
| JP-8245542-A | — | — | None | — | — | JP | disclosed |
| JP-8259510-A | — | — | None | — | — | JP | disclosed |
| JP-7188076-A | — | — | None | — | — | JP | disclosed |
| CN-110372538-B | Synthesis method of 2, 6-dichloro-3-fluorobenzonitrile | 浙江吉泰新材料股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112573990-B | Preparation method of 4-halogenated-3-fluorotoluene | 沈阳中化农药化工研发有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-0713862-A2 | Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds | BAYER AG (DE) | 1996-05-29 | — | — | EP | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| JP-H07188076-A | PRODUCTION OF 3-FLUORO-4,6-DICHLOROTOLUENE | BAYER AG | 1995-07-25 | — | — | JP | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |